Some common skin diseases - Treatment of Lupus erythematosus

Is a chronic disease with no cure, the treatment of systemic lupus erythematosus and systemic systems. Basically means to prevent disease outbreaks and reduce the extent and duration of the illness affects them .--------------

Is a chronic disease with no cure, the treatment of systemic lupus erythematosus and systemic systems. Basically means to prevent disease outbreaks and reduce the extent and duration of the illness affects them. Treatment with corticosteroids can and anti-malarial drugs. Some types of lupus glomerulonephritis as proliferative glomerulonephritis requires pervasive drug toxicity such as cyclophosphamide and mycophenolate cells. The drugs Because the symptoms and the body systems are affected very differently, to assess the severity of each person to be treated effectively. Where light and decrease may not need treatment. If necessary you can use anti-inflammatory drugs and anti-malarial drugs sterois. Anti rheumatic disease changes Anti-rheumatic drugs change disease (Disease-Modifying antirheumatic drug - DMARDs) are used to prevent the outbreak of disease, disease progression, and reduce the need for the use of steroids; itself outbreaks are treated with corticosteroids. The common types of DMARDs is the anti-malarial drugs such as plaquenil and immunosuppressive agents (eg, methotrexate and azathioprine). Hydroxychloroquine is anti-malarial drugs are FDA approved for the treatment of physical symptoms, dermatological or joints. Hydroxychloroquine has relatively few side effects, and may increase the survival rate of patients with lupus erythematosus system. Cyclophosphamide is used for cases of severe glomerulonephritis or complications ruin other agencies. Ax mycophenolic it is also used to treat lupus glomerulonephritis, but not yet FDA-approved for FDA inspection reports are suspect potential birth defects if pregnant women take this medicine. The immunosuppressive drugs In severe cases, the drugs need to regulate the activity of the immune system (mainly corticosteroids and immunosuppressive drugs) to control the disease and prevent relapse episodes (or the outbreaks). Depending on the dose, patients taking steroids may be Cushing's syndrome and the side effects such as obesity, facial edema, diabetes, appetite, insomnia, and osteoporosis. The side effects can be reduced if large initial dose is reduced, but if the long-term use even low doses can also cause hypertension and Cataract. There are many kinds of new immunosuppressive drugs being tested in the treatment of this disease. Instead of inhibiting an immune system of nonspecific mechanisms of corticosteroid, new drugs focused to meet each type of immune cell. Some drugs have been FDA approved for the treatment of rheumatoid arthritis drug Belimumab More and rituximab. Analgesic Because a large proportion of patients with lupus erythematosus suffer System   chronic pain, your doctor might prescribe stronger pain medications if the non-prescription drugs (mainly non-steroidal anti-inflammatory drugs - NSAIDs) are not effective. NSAIDs such as indomethacin and diclofenac strengths are often contraindicated for patients because they increase the risk of kidney failure and heart failure. The average pain can be treated with a mild anesthetic as dextropropoxyphene and co - codamol. But moderate to severe pain to use addictive drugs like hydrococdone stronger or more prolonged effect as ox codone, MS Contin, or Methadone. The patch on the skin containing duragesic Fentannyl also widely used in the treatment of chronic pain due to prolonged duration of action and ease of use. When addictive drugs are prolonged use may lead to drug tolerance, dependence and addiction medicine. The drug is not a major concern because the symptoms often can not completely heal. So the treatment of chronic pain with narcotic drugs for life (accompanied by a redefinition of content suitable for routine drug) is usually popular. The determination of the content is also frequently recurring to any treatment regimen using addictive drugs. Lifestyle Changes Major changes in patients with SLE system is to avoid sunlight because sunlight do worse. If patients have to use other drugs not related to lupus, it should be used only if the medicine is certainly not do worse. Occupational exposure to silica, pesticides and mercury can also sicker Kidney transplant Kidney transplantation is a common treatment method in cases of end-stage renal disease, is one of the complications of lupus glomerulonephritis, but then 30% of patients still relapse. Prevention Since SLE is not well understood system should also not be prevented, however, when you are sick, we can minimize the damage, enhance the quality of life of patients by preventing the onset phase . The warning signs for an imminent attack of the disease may include: fatigue, pain, rash, fever, abdominal pain, headache, and dizziness. If you recognize the early warning signs and regular contact with the doctor, the patient can be more active, less pain and reduce the number of visits to the hospital. Since the lifespan of patients with lupus erythematosus system is increased, the likelihood of complications and more for: cardiovascular disease, inflammation, osteoporosis, and cancer. There should be standard precautions and check-related illnesses because of the increased risk of side-effects of drugs. In particular, physicians and patients should always alert for cancer-related immune system Complications of pregnancy Although the majority of mothers with lupus erythematosus systems usually have healthy babies, mothers with the disease during pregnancy should continue to monitor the treatment until birth. Lupus is a rare congenital, but if determined to be the case with high-risk pregnancies may have treatment before and after birth. In addition, the attack of the disease can occur during pregnancy, if treated properly can maintain good health for mothers longer. The pregnant woman with anti-Ro (SSA) or anti-La (SSB) often do echocardiography during weeks 16 to 30, to monitor the heart and vascular system around. The methods of birth control and contraception commonly prescribed for women with this disease for pregnant in growing stage disease can be dangerous. Lupus glomerulonephritis is the most common complication. Children live birth rate is about 72.7%; The most common cause of miscarriage is caused miscarriages and stillbirths. The effects of pregnancy than when patients have episodes of illness during pregnancy. Prognosis SLE system does not curable, but can be treated dd Article. In the 1950s, the majority of patients live more than 5 years. Advances in diagnosis and treatment have increased survival rates, at present, more than 90% of patients can live to be over 10 years, and many people can live without symptoms. The prognosis in men, and children are often worse in women; However, if symptoms appear after age 60, the disease is usually more benign. Premature death within 5 years is usually caused by failure of internal organs or inflammation caused by too heavy. But there are two reasons can be controlled if diagnosed and treated early. The risk of death is higher than 5 times higher than normal at the end, because cardiovascular disease is caused by corticosteroid drugs. Cardiovascular diseases are also the cause of death in patients with lupus erythematosus system. To reduce the risk of heart disease, to prevent and treat radically high blood pressure and high cholesterol. Only use steroid drugs at the lowest dose in the shortest time possible, and to use other drugs to reduce symptoms if possible. Serum creatinine levels high, high blood pressure, kidney failure syndrome (nephrotic syndrome), anemia and decreased albumin in the blood are not good predictors. Antinuclear antibody test (ANA) is the most sensitive screening test to evaluate, and anti-Smith antibody test is the most specific. Double-stranded DNA antibodies is relatively nonspecific and often change with disease progression, so the concentration of double-stranded DNA is sometimes used to drop the attacks of the disease or response to treatment. Epidemiology Rate system SLE vary between countries, ethnic, gender, and change over time. In the United States, the prevalence of the disease is about 53 per 100,000 people, which means that approximately 159,000 of the total 300 million people in the US are infected. In Northern Europe, the rate is about 40 per 100,000 people Patients tend more and more severe in the community who are not of European descent. This rate of up to 159 per 100,000 in African communities in the Caribbean. Systemic lupus erythematosus, as well as other autoimmune diseases, affecting more women than men, with a ratio of about 9: 1. The incidence of this disease in the United States increased from 1.0 in 1955 to 7.6 in 1974. However, this rate increase is not clear due to better diagnosis or due to increased incidence of disease